IGNOU MBC 2 SOLVED ASSIGNMENT

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MBC 2 2025 - English

ASSIGNMENT

Cell and Molecular Biology

Course Code: MBC-002

Assignment code: MBC-002/TMA/2025

Maximum marks: 100

Note: Attempt all the questions. Write the answers in your own words; do not copy from the course material. Draw the figures/flowcharts/tables wherever required.

1. a) Define the following terms:

i) Nucleoplasm

ii) Mitochondrial cristea

iii) Photosynthesis

iv) Microtubules

b) Write a brief account note on extracellular matrix (ECM).

2. Describe the different cell adhesion molecules.

3. a) What are the check points? Describe their role in regulation of cell cycle.

b) Differentiate between apoptosis and necrosis.

4. a) Discuss the Singer and Nicholson's Model of Plasma membrane.

b) Explain:

i) Cot Curve

ii) Pseudogenes

5. a) What are the different levels of packaging of DNA into higher order structures? Discuss.

b) Elucidate the rolling circle mechanism of DNA replication.

6. Explain the structure and functions of the following:

a) Helix-Turn-Helix (HTF) motif.

b) E. Coli DNA polymerase III

a) Briefly discuss the structure and roles of E. Coli. RNA polymerase.

b) Elaborate the post transcriptional RNA processing in eukaryotes?

8. a) What is Wobble hypothesis? Write its significance.

b) Describe the steps involved in the initiation of bacterial translation

9. Write a short note on the following:

a) Mutation

b) Catabolite repression

10. a) Describe the modifications in DNA and Histones.

b) Discuss the regulation of gene involved in organism development.

MBC 002 (January 2026 - July 2026) - ENGLISH

ASSIGNMENT

Cell and Molecular Biology

Course Code: MBC-002

Assignment code: MBC-002/TMA/2026

Maximum marks: 100

Note: Attempt all the questions. Write the answers in your own words; do not copy from the course material. Draw the figures/flowcharts/tables wherever required.

1.  a) Define the following terms:

i) Apoptosis

ii) Plasmodesmata

iii) Crossing-over

iv) 30nm fiber

b) Explain the structure and function of peroxisomes.

2. Describe the components of extracellular matrix.

3. a) Explain how do chromosomes behave during the mitosis.

b) Write an overview on signaling molecules.

4. Discuss the following:

a) C- value paradox

b) Chromosome banding patterns

5. a) Explain the role of DNA double helix in DNA protein complex.

b) Compare the prokaryotic DNA replication and eukaryotic DNA replication.

6. Discuss:

a) Basic transcription unit

b) RNA splicing

7. a) Briefly discuss the basic features of the genetic code.

b) Distinguish between prokaryotic translations and eukaryotic translation.

8. a) Mention the inherited disorders of DNA repair pathways.

b) Write a detailed note on the Tryptophan operon.

9. Write a short note on the following:

a) Modification in DNA and Hisntones

b) Hot spot Mutation

10. Explain the following:

a) Dynamic behavior of microtubules

b) Structural maintenance of chromosomes

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