IGNOU MBC 5 SOLVED ASSIGNMENT

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MBC 5 2025 - English

ASSIGNMENT

CONCEPTS AND CONNECTIONS IN METABOLISM

Course Code: MBC-005

Assignment code: MBC-005/TMA/2025

Maximum marks: 100

Note: Attempt all questions. The marks for each question are indicated against it.

Write the answers in your own words; do not copy from the course material.

Note: Attempt all questions. The marks for each question are indicated against it. Write the answers in your own words; do not copy from the course material.

PART-(A)

1. Give an overview of Biological electron donors and acceptors [10]

2. What is Cori’s Cycle? How is it regulated?

3. Give a schematic representation of metabolic reactions in Krebs cycle? Explain its significance?

4. Draw metabolic pathway of the biosynthesis of saturated fatty acid.

OR

b) Explain the following:

i) Gluconeogenesis

ii) Ketogenesis

5. Explain the biosynthesis of cholesterol from Acetyl-CoA?

PART- (B)

6. Describe the Glucose Alanine cycle.

7. Discuss the inborn errors of amino acid metabolism.

8. Give an overview of Amino acid biosynthesis.

OR

Explain any two of the followings:

a) Purine catabolism

b) Biosynthesis of Nucleotide coenzymes

c) Electron flow from NADPH to ribonucleotide reductase

9. Describe the denovo synthesis of Purine nucleotides

10. Write notes on the followings:

a) Gout

b) Metabolic profile of Muscle

MBC 005 (January 2026 - July 2026) - ENGLISH

ASSIGNMENT

CONCEPTS AND CONNECTIONS IN METABOLISM

Course Code: MBC-005

Assignment code: MBC-005/TMA/2026

Maximum marks: 100

Note: Attempt all questions. The marks for each question are indicated against it.

Write the answers in your own words; do not copy from the course material.

PART-(A)

Marks: 50

1. a) Discuss the role of ATP and cellular energy currency.

b) State the second law of thermodynamics. How is it applicable on living organisms?

2. a) What is the difference between hexokinase and glucokinase?

b) Give an example of substrate level phosphorylation reaction in glycolysis.

c) Enlist the enzyme components of pyruvate dehydrogenase complex and state their role.

d) Explain the role of debranching enzyme during glycogenolysis and draw the reactions.

3. a) What is biochemical basis and symptoms of essential pentosuria?

b) Explain two tests used for detection of lactose intolerance.

4. a) How does mobilization of lipids stores in adipose tissue to the target tissues take place?

b) State the differences between mitochondrial and peroxisomal ẞ-oxidation pathways.

5. a) How is fatty acid synthesis regulated in animals by covalent modification?

b) Explain the dihydroxy acetone phosphate (DHAP) pathway of triglyceride synthesis.

PART- (B)

6. a) Describe the concept of Ammonia Assimilation.

b) Classify amino acids based on the fate of their carbon skeleton.

7. Discuss the biosynthesis of non-essentail amino acids of serine family.

8. Explain the de novo synthesis pathway of purine ribonuleotides.

9. (a) What are the inhibitors of nucleotide synthesis?

(b) Compare the degradation of purines and pyrimidines.

10. Describe diagnosis and symptoms of:

i) Gout

ii) Phenyketonuria

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