IGNOU MBCE 17 SOLVED ASSIGNMENT

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MBCE 17 2025 2026 - English

Assignment

OMICS

Course Code: MBCE-017

Assignment code: MBCE-017/TMA/2025-26

Maximum marks:100

Note: Attempt all questions.

PART-(A)

1. (a) Write briefly the aim and different branch of omics.

(b) Explain the Gene Annotation and its importance

2. (a) Discuss Illumina Sequencing.

b) Describe the molecular phylogeny.

3. (a) What are regulatory RNAs.

(b) With the help of diagram, explain the adapter trimming.

4. Describe the steps involved in DNA microarray in details.

5. Write short notes on any two of the following:

a) Saccharomyces cerevisiae as an experimental genomic model

b) Computational prediction of MiRNA target genes

c) National Center for Biotechnology Information (NCBI)

PART-(B)

6. Describe the protein-protein interactions in proteomics.

7. (a) Explain the principle and applications of the Two-Dimensional (2D) Gel Electrophoresis.

(b) What is Homology modeling? Discuss briefly any one tool used in homology modelling.

8. (a) Define metabolomics and discuss its different types.

(b) Differentiate between Mass spectrometry and Nuclear Magnetic Resonance (NMR).

9. (a) Compare the Structure-Based Drug Design (SBDD) Ligand-Based Drug Design (LBDD).

(b) Enlist the basic steps of Molecular Docking.

10. Write short notes on any two of the following:

a) MetaboAnalyst 5.0

b) Metabolic Network

c) RCSB Protein Data Bank (PDB)

MBCE 017 (January 2026 - July 2026) - ENGLISH

Assignment
OMICS
Course Code: MBCE-017
Assignment code: MBCE-017/TMA/2026-27
Maximum marks: 100
Note: Attempt all questions. Write answers in your own words.
PART-(A)
1. (a) Write briefly the evaluation of OMICS. 
(b) Explain the genome mapping 
2. (a) Discuss sequence alignment and is importance. 
b) Describe the Nanopore DNA sequencing 
3. (a) Describe Cap analysis of gene expression. 
(b) With the help of diagram, explain the Shotgun sequencing. 
4. Describe the Data processing in DNA microarray in details.
5. Write short notes on any two of the following: 
a) Drosophila Melanogaster as an experimental genomic model
b) Single Cell Transcriptomics
c) DNA databank for Japan

PART-(B)
6. Describe the proteomics and its types 
7. (a) Explain the MS-MALDI. 
(b) What is metabolome? Discuss briefly plant metabolomics. 
8. (a) Discuss the GC-MS in metabolomics studies. 
(b) Explain the protein microarray. 
9. (a) Discuss the pharmcophore features.
(b) Enlist the basic steps of Pharmacist software. 

10. Write short notes on any two of the following: 
a) KEGG
b) IMPPAT
c) Swiss PDB viewer 

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