IGNOU MSCANCHEM MCH 15 SOLVED ASSIGNMENT

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MCH 15 2025 - English

Tutor Marked Assignment BIOLOGY FOR CHEMISTS (MCH-015)

Course Code: MCH-015

Assignment Code: MCH-015/TMA/2025

Note: Attempt all questions. The marks for each question are indicated against it.

Maximum Marks: 100

1. a) What is the name of the system of classification applied for the domains of life? List the common features of prokaryotes and eukaryotes.

b) Which cell organelle is called the "control centre"? Describe its composition.

2. a) Write the step wise reactions of formation of a glycoside taking glucose as an example.

b) What are hormones? Name the classes of steroid hormones along with their important functions.

3. a) Describe how the cell membrane regulates the movement of various molecules into and out of the cell.

b) Differentiate between the essential and non essential amino acids. Describe the amphoteric nature of amino acids.

4. a) Explain the geometry of the peptide backbone. Illustrate your answer.

b) Describe the tertiary structure of proteins in terms of the bonds and forces that stabilise the structure.

5. a) Why the metabolism is called the 'intermediary metabolism'? Describe the convergent and divergent nature of metabolism.

b) Explain what is meant by high energy phosphate compounds and what their significance is in the living systems.

6. a) What is EMP pathway? Explain the isomerisation reaction of glycolysis giving the catalyst involved.

b) Explain the role of constituent enzymes of pyruvate dehydrogenase complex involved in the conversion of pyruvate into acetyl-CoA.

7. a) What are ketone bodies? Explain their significance to human beings.

b) Draw a diagrammatic sketch of the urea cycle indicating the products and enzymes involved.

8. a) Give a comparative account of purine and pyrimidine nucleotide degradation.

b) Define immunity. Differentiate between innate and acquired immunity.

9. a) What is the significance of antigen-antibody interaction? Describe in brief the mechanisms involved in antigen-antibody interaction.

b) Name the enzymes involved in DNA replication and describe their role in this process.

10. Write short notes on the following:

a) Water and electrolyte balance in living systems

b) Blood group substances

c) Nucleosides and nucleotides

d) Homeostasis

MCH 015 (January - 2025) - ENGLISH

Tutor Marked Assignment Biology for Chemists

Course Code: MCH-015

Assignment Code: MCH-015/TMA/2025-26

Maximum Marks: 100

Note: Attempt all the questions. The marks for each question are indicated against it.

1.

a) What will be the sequence of separation of the organelles, ribosomes, nucleus and mitochondria in a tissue homogenate when subjected to centrifugation. Explain your answer.

b) Briefly describe different modes through which cell membrane controls the transport of ingoing and outgoing molecules?

2.

a) What are anomers? Explain the existence of anomers in sugars taking D-glucose as an illustrative case.

b) Discuss the classification of carbohydrates on the basis of number of saccharide units giving example of each class.

3.

a) A fat has low iodine number and a high saponification number. What do you infer from that? What are essential fatty acids and why are they essential?

b) Explain the 'fluid mosaic model' for membrane structure.

4.

a) Draw the structure of a dinucleotide of adenosine - 5'-phosphate and uridine - 5'-phosphate. In which process of protein biosynthesis, t RNA is involved? Illustrate the gross structural features of t - RNA. Indicate the different regions.

b) Write a short note on the different forms of RNA.

5.

a) What are the structural and functional differences between myoglobin and haemoglobin?

b) How is the standard free energy for chemical reactions different from the standard free energy for biochemical reactions?

6.

a) With the help of an example explain the significance of coupling in biological reactions.

b) Explain homeostasis. How is the water balance maintained in the body?

7. Write short notes on the following:

a) Mitchell's chemiosmotic hypothesis

b) ATP - the energy currency of cell

8. a) Compare the functions of RNA polymerase with DNA polymerase. How is transcription terminated?

b) Explain the mechanism of action of the enzyme aconitase on citrate in TCA cycle.

9. Compare the following:

a) Energetics of metabolic oxidation of glucose and a fatty acid

b) Biosynthesis and ẞ-oxidation of fatty acids

10.

a) List different types of antibodies. What are the gross structural features of an antibody molecule? Discuss any one mechanism by which antibodies interact with antigens.

b) Discuss the "specific immunologic tolerance" theory of immune response.

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